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目的 :分析乙型肝炎多重感染的病原学类型及其临床特征。方法 :乙型肝炎多重感染患者 94例 ,其中三重感染 80例 ,四重感染 14例 ,用日期随机法抽取同期单纯乙型肝炎 10 0例作为对照组进行分析。结果 :乙型肝炎多重感染以丁肝病毒 (HDV)、巨细胞病毒 (CMV)与甲肝病毒 (HAV)者居多 ,分别为 79.8%、5 1.1%、40 .4% ,17例急性肝炎患者中有 16例合并HAV感染。乙型肝炎多重感染组中急性肝炎、慢性重型肝炎与慢性肝炎 (重度 )的比例明显高于单纯感染组 ,而慢性肝炎 (轻度 )与肝硬化明显低于单纯感染组 (P <0 .0 0 1)。结论 :与单纯感染相比 ,乙型肝炎多重感染肝功能损害严重 ,有重症化倾向 ,易急性发作
Objective: To analyze the etiological types and clinical features of multiple hepatitis B infection. Methods: Ninety-four patients with multiple hepatitis B infection, including 80 cases of triple infection and 14 cases of tetracycline infection, were randomly divided into two groups. Results: The majority of hepatitis B infections were hepatitis C virus (HDV), cytomegalovirus (CMV) and hepatitis A virus (HAV), accounting for 79.8%, 51.1% and 40.4% respectively. Of the 17 patients with acute hepatitis 16 cases had HAV infection. The proportion of acute hepatitis, chronic severe hepatitis and chronic hepatitis (severe) in multiple hepatitis B infection group was significantly higher than that in simple infection group, but chronic hepatitis (mild) and cirrhosis were significantly lower than those in simple infection group (P <0. 0 0 1). Conclusion: Compared with simple infection, hepatitis B multiple infection has serious damage to liver function, with severe tendency and acute exacerbation