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选择１２６名中学生，随机分成４组．实验组皮内接种０．１ｍｌ疫苗，６０天后按常规程序接种；对照组只按常规程序接种；另两组为２—１─１和３—１程序组．研究结果表明，４组在接种后第７天抗体阳性率分别为５２．９４％：３．３３％、２０．００％和１５．６３％；第１４天分别为１００％、６６．６７％、６３．３３％、和７５．００％。实验组的抗体阳性率显著高于其他３组．第２８天时４个组的抗体阳性率十分接近。４个组的抗体水平也存在同样趋势。提示：小剂量疫苗可加速常规免疫程序抗体的产生。
126 high school students were selected and randomly divided into 4 groups. The experimental group was inoculated intradermally with 0.1 ml vaccine, and was inoculated routinely 60 days later. The control group was vaccinated only according to routine procedures. The other two groups were 2-1 ─ 1 and 3-1 program groups. The results showed that the positive rates of antibody on the 7th day after inoculation were 52.94%, 3.33%, 20.00% and 15.63% in the four groups, 100% and 66.67% on the 14th day respectively, 63.33%, and 75.00%. The positive rate of antibody in the experimental group was significantly higher than the other three groups. On the 28th day, the antibody positive rate of the four groups was very close. Antibody levels in the four groups also showed the same trend. Tip: A small dose of vaccine can speed up the production of antibodies in routine immunization programs.