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甘露醇是一种常用的渗透性利尿剂,我们自1990年4月至1993年3月用甘露醇治疗了各种原因引起的脑水肿147例。在用药期间有24例发生了甘露醇性肾病。现报告如下。1 资料与方法:①病例来源:本组病人均为我院住院患者。男98例,女49例.年龄24岁—76岁,病种分布:脑梗塞109例,脑出血25例,蛛网膜下腔出血9例,CO 中毒4例,原有肾脑病者未列入本组。②诊断标准:在应用甘露醇过程中,出现无明显原因的血尿和(或)尿量减少及 BUN 增高,并能排除肾前性、肾性及感
Mannitol is a common osmotic diuretic, and we treated 147 patients with various causes of brain edema with mannitol from April 1990 to March 1993. During the medication, 24 patients had mannitol nephropathy. The report is as follows. 1 Materials and Methods: ① Case Source: The patients were hospitalized patients in our hospital. Male 98, female 49. Aged 24 years old to 76 years old, the distribution of the disease: cerebral infarction in 109 cases, 25 cases of cerebral hemorrhage, 9 cases of subarachnoid hemorrhage, CO poisoning in 4 cases, the original nephrotic were not included This group. ② diagnostic criteria: in the application of mannitol, there was no obvious reason for hematuria and (or) decreased urine output and increased BUN, and can rule out prerenal, renal and flu