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目的探讨低剂量核辐射暴露、肥胖、腹部型肥胖对核电站工人全血细胞计数的影响。方法收集某核电站1 388名男性在职工人的健康检查资料,检测工人的外周血总白细胞、白细胞各分类、红细胞、血小板计数。体块指数≥30 kg/m2定义为肥胖,男性腰围≥90 cm定义为腹部型肥胖。结果工人工龄增高是总白细胞计数增高、单核细胞百分比降低的独立危险因素,肥胖是总白细胞计数增高的独立危险因素,腹部型肥胖是总白细胞、红细胞、血小板计数增高和嗜碱性粒细胞百分比降低的独立危险因素(P<0.05)。按工龄分层后,1~9 a工龄组肥胖工人总白细胞计数高于非肥胖工人,1~9 a、10~19 a工龄组腹部型肥胖工人总白细胞计数高于非腹部型肥胖工人,差异均有统计学意义(P<0.01)。结论低剂量核辐射长期暴露可能与核电站工人外周血总白细胞数增高有关,患肥胖或腹部型肥胖可能加重核辐射对外周血细胞数的影响。
Objective To investigate the effects of low dose radiation exposure, obesity and abdominal obesity on the whole blood count of nuclear power station workers. Methods A total of 1 388 male workers in a nuclear power station were collected for health checkup. The total white blood cell count, white blood cell count, red blood cell count and platelet count of workers were measured. Body mass index ≥30 kg / m2 is defined as obesity, waist circumference ≥ 90 cm is defined as abdominal obesity. Results Workers’ working age was an independent risk factor of total white blood cell count increased and monocyte percentage decreased. Obesity was an independent risk factor of total white blood cell count. Abdominal obesity was the ratio of total white blood cells, erythrocytes, platelet count and basophil percentage Decreased independent risk factors (P <0.05). After stratified by length of service, the total white blood cell count of obese workers from 1 to 9 years of age was higher than that of non-obese workers, and the total leukocyte counts of abdominal obese workers from 1 to 9 years and 10 to 19 years of age were higher than those of non-obese obese workers All were statistically significant (P <0.01). Conclusion Long-term exposure to low dose radiation may be related to the increase of total white blood cell count in peripheral blood of nuclear power station workers. Obesity or abdominal obesity may aggravate the influence of radiation on peripheral blood cells.