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目的:探讨2009～2011年江阴市新生儿血清苯丙氨酸及促甲状腺素筛查情况。方法:回顾性分析2009～2011年新生儿血清苯丙氨酸及促甲状腺素筛查情况。新生儿于出生72 h,充分母乳喂养后采足跟血检测血清苯丙氨酸及促甲状腺素水平,对可疑阳性者通知其家属及时进行复查确诊。结果:2009～2011年江阴市活产儿60 790例,共筛查新生儿59 210例,总筛查率为97.4%;三年间全市总筛查率逐年上升,差异具有统计学意义(P<0.05);59 210名被筛查者中,初检阳性者941例,召回复查者694例,召回率73.8%,确诊阳性者34例。结论:江阴市新生儿血清苯丙氨酸及促甲状腺素筛查率逐渐增高,召回率较低。
Objective: To investigate the screening of serum phenylalanine and thyrotropin in neonates from 2009 to 2011 in Jiangyin City. Methods: A retrospective analysis of 2009 to 2011 newborns serum phenylalanine and thyroid-stimulating hormone screening. Neonates at 72 h after birth, full of breast-feeding after heel and blood test for detection of serum phenylalanine and thyroid-stimulating hormone levels, the suspicious positive notification to their families timely review confirmed. Results: 60 790 live births were detected in Jiangyin City from 2009 to 2011, 59 210 newborns were screened and the total screening rate was 97.4%. The total screening rate increased year by year in three years (P <0.05) ). Of the 59 210 screened subjects, 941 were positive for the first seizure, 694 were recalled, and the recall rate was 73.8%. There were 34 confirmed positive cases. Conclusion: The screening rates of serum phenylalanine and thyrotropin in newborn infants of Jiangyin are gradually increasing, and the recall rate is low.