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应用参附注射液替代或部分替代肾上腺皮质激素治疗小儿特发性血小板减少性紫癜(ITP),开辟新的治疗途径。方法采用中西医结合的方法,观察参附注射液治疗31例ITP患儿的疗效,并与同期用激素治疗的27例及对症治疗的31例ITP患儿进行比较。结果参附注射液治疗组,在治疗25d时血小板回升和CD4+/CD8+回升明显高于激素组及对症治疗组(P<0.01),且无副作用。结论应用参附注射液或加用肾上腺皮质激素治疗ITP优于肾上腺皮质激素,值得推广。
Application of Shen Fu injection instead of or partial replacement of adrenal cortex hormones in children with idiopathic thrombocytopenic purpura (ITP), open up new avenues of treatment. Methods The therapeutic effect of Shenfu injection on 31 children with ITP was observed by the method of integrated traditional Chinese and western medicine. The results were compared with 27 patients treated with steroid and 31 patients with symptomatic treatment of ITP during the same period. Results Shenfu injection treatment group, 25d platelet rise and CD4 + / CD8 + recovery was significantly higher than the hormone group and symptomatic treatment group (P <0.01), and no side effects. Conclusion Shenfu injection or addition of corticosteroids is superior to adrenocorticotropic hormone treatment of ITP, it is worth promoting.