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目的：比较维拉帕米与山莨菪碱治疗肾绞痛的疗效。方法：１５３例肾绞痛病人随机分为３组。Ａ组５４例（男性３５例，女性１９例；年龄３５±ｓ９ａ）采用维拉帕米２０ｍｇ；Ｂ组４８例（男性３０例，女性１８例；年龄３４±７旬采用维拉帕米８０ｍｇ；Ｃ组５１例（男性３２例，女性１９例；年龄３７±１０ａ）采用山莨菪碱２０ｍｇ。以上３个药分别加入５％葡萄糖液２５０ｍＬ，静脉滴注，且于１ｈ滴完。结果：Ａ组总有效率８９％，Ｂ组９２％，Ｃ组７３％；Ａ，Ｂ２组分别与Ｃ组比较，差别均有显著意义（Ｐ＜０．０５）。Ｂ组显效率明显优于Ａ或Ｃ组（Ｐ＜０．０５）。结论：Ｂ（维拉帕米８０ｍｇ）组疗效最佳。
Objective: To compare the efficacy of verapamil and anisodamine in the treatment of renal colic. Methods: 153 patients with renal colic were randomly divided into three groups. A group of 54 patients (35 males and 19 females; age 35 ± s9a) with verapamil 20mg; B group 48 patients (30 males and 18 females; aged 34 ± 7 days with verapamil 80mg; 51 patients in group C (32 males and 19 females, age 37 ± 10a) were treated with anisodamine 20 mg.The above three drugs were respectively added into 250 mL 5% dextrose solution intravenously and dripped at 1 h.Results: Group A The total effective rate was 89% in group B, 92% in group C and 73% in group C. The difference between group A and group B was significant (P <0.05), and group C was significantly better than group A or C (P <0.05) .Conclusion: B (verapamil 80mg) has the best curative effect.