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Lennox Gastaut综合征(LGS)是一种儿童期顽固性癫痫。通过50例LGS患儿的长期随访观察,发现LGS病因是多样的。临床特点是紧张性发作、假性失神、肌阵挛、失张力性发作等。典型EEG是低于3/s慢尖慢波。本病治疗困难,未发现任何特效疗法,预后极差。提出对LGS的诊断意见,并推测其病生理的可能变化机制。
Lennox Gastaut syndrome (LGS) is a childhood intractable epilepsy. Long-term follow-up of 50 cases of LGS children found that the cause of LGS is diverse. Clinical features are tense seizures, hypocrisy, myoclonus, loss of seizures and more. Typical EEG is slower than 3 / s slow-wave. Treatment of this disease is difficult, did not find any special effects therapy, poor prognosis. Proposed the diagnosis of LGS, and speculated that the possible mechanism of the disease physiology.