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目的对药物的不良反应原因进行归纳总结,为临床合理用药提供可行性意见和可靠依据。方法抽取在2008年12月至2010年12月这两年时间里,在我院就诊且接受药物治疗的患者中,用药后出现不良反应的患者病例147例,对其所产生的不良反应进行归纳总结,对不良反应产生的原因进行系统分析,并对临床上如何进行安全用药进行总结。结果研究结果显示,在用药后出现不良反应的患者147例中,患者在用药后主要出现的不良反应类型可以概括为过敏反应、毒性反应、特异性反应、二重感染等四种类型;导致患者在用药后出现不良反应的因素有药物因素、患者因素、其他方面因素等几个方面。结论临床必须对药物在服用后会带来的不良反应情况进行充分的了解,对造成用药后不良反应的因素进行有效控制,这样才能使患者在服药后尽可能少的出现用药后的不良反应。
Objective To summarize the causes of adverse drug reactions and provide feasible advice and reliable basis for clinical rational drug use. Methods A total of 147 patients with adverse reactions after medication were enrolled in this study during the two years between December 2008 and December 2010. Among the patients treated in our hospital and treated with drugs, adverse reactions were summarized In summary, the causes of adverse reactions were systematically analyzed and the clinical use of safe drugs was summarized. Results The results showed that among the 147 patients with adverse reactions after treatment, the main types of adverse reactions after treatment were summarized as allergic reaction, toxic reaction, specific reaction and double infection. In the adverse drug reactions after the drug factors, patient factors, other aspects of several aspects. Conclusions The clinical needs to fully understand the adverse reactions caused by the drugs after taking the drugs and to effectively control the factors that cause the adverse reactions after the drugs are administered. In this way, the patients can receive as little adverse reactions as possible after taking the drugs.