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渗出性多形红斑的重型称斯-琼(Stevcn-John-son)综合征,小儿较为少见,常易与发疹性热性病混淆,结合我们近年遇到的5例,探讨诊断与治疗问题。临床资料5例中男2例,女3例;年龄1.5～3岁3例,5、12岁各1例;前驱感染有麻疹、扁桃体炎、未明病原的败血症、白色葡萄球菌(凝固酶阳性)败血症及皮肤感染;3例病前曾有1～2种用药史,如磺胺、青霉素类、鲁米那、阿司匹林。发病与前驱感染的间隔时间:2例为4～7日,2例为26～29日,1例发生于败血症病程第3周。发病与用药的间隔时间为7～17日。初次诊断:麻疹2例、剥脱性皮炎、红斑狼疮、川崎病再发,无1例初次即诊断本病者。
Exudative erythema multiforme heavy Scintikenn-Joan syndrome (Stevcn-John-son), children are relatively rare, often easy to be confused with rash fever, combined with the five cases we encountered in recent years, to explore the diagnosis and treatment issues . Clinical data of 5 cases, 2 males and 3 females; aged 1.5 to 3 years old in 3 cases, 5,12-year-old in each case 1; pre-infection with measles, tonsillitis, unexplained pathogenic sepsis, Staphylococcus aureus (coagulase-positive) Sepsis and skin infections; 3 patients had 1 to 2 kinds of medication before the history of medication, such as sulfonamides, penicillins, luminal, aspirin. The interval between onset and infection was 2 to 4 days, 2 to 26 to 29 days, and 1 to sepsis in the third week. The incidence and medication interval of 7 to 17 days. Initial diagnosis: 2 cases of measles, exfoliative dermatitis, lupus erythematosus, Kawasaki disease recurrence, no case of first diagnosis of the patient.