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肺癌在我国肿瘤发病率中位居首位,近年来呈现增高趋势。小细胞肺癌(small cell lung cancer,SCLC)约占肺癌的20%～25%,恶性程度高,生长迅速,转移发生早,5年总体生存率不足10%。肿瘤标志物检测在肺癌的早期诊断、病理分型、疗效评估及复发监测中发挥重要作用。但是单一肿瘤标志物在临床检测中存在敏感度和特异度不足的缺点,我们通
Lung cancer ranks first in the incidence of cancer in China, showing an increasing trend in recent years. Small cell lung cancer (SCLC) accounts for about 20% -25% of lung cancer. It has a high degree of malignancy, rapid growth, early metastasis and less than 10% overall 5-year survival rate. Tumor markers detection plays an important role in the early diagnosis, pathological classification, curative effect evaluation and recurrence monitoring of lung cancer. However, the single tumor markers have the shortcomings of lack of sensitivity and specificity in clinical testing.