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甲巯丙脯酸(captopril)是一口服有效的血管紧张素转化酶抑制剂。经国内外临床实践证明,具有良好的降压效果,已作为抗高血压药应用于临床。由于扩血管药对慢性心功不全的疗效引起临床的重视,国外已有不少学者,将甲巯丙脯酸亦试用于慢性心功不全,取得了相当满意的疗效。其结果表明,本品具有作用强,毒性低,可口服,无耐受性等优点。本文主要对其治疗慢性心衰时血液动力学的效应及其作用机理作一简介。一、对血液动力学的影响甲巯丙脯酸可使慢性心功不全时多数血液动力学指征,产生明显的变化,使决定心脏泵
Captopril is an orally available angiotensin-converting enzyme inhibitor. The clinical practice at home and abroad have proved that with good antihypertensive effect, has been used as antihypertensive drugs in clinical. Due to vasodilator drugs on the clinical efficacy of chronic heart failure caused by clinical attention, many foreign scholars, the captopril will also be used in chronic heart failure, and achieved very satisfactory results. The results show that the product has strong effects, low toxicity, can be oral, non-tolerant and so on. This article is mainly about the treatment of chronic heart failure hemodynamic effects and its mechanism of action for a brief introduction. First, the impact on hemodynamics Captopril can make the most of hemodynamic indications of chronic heart failure, resulting in significant changes in the decision to heart pump