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目的:观察卡维地洛对急性心肌梗死后心功能及心室重构的影响。方法:50例急性心肌梗死患者,在急性心肌梗死常规治疗基础上给予卡维地洛口服,递增剂量口服。分别于治疗前、后24周超声心动图,了解心脏功能与心脏结构变化以及肝肾功能。结果:治疗后24周与治疗前比较心功能改善、心室重构逆转均达统计学意义(P<0.05)。结论:卡维地洛可逆转急性心肌梗死患者心室重构并有效改善心功能。
Objective: To observe the effect of carvedilol on cardiac function and ventricular remodeling after acute myocardial infarction. Methods: Fifty patients with acute myocardial infarction were given carvedilol orally on the basis of conventional treatment of acute myocardial infarction. Respectively before and 24 weeks after echocardiography to understand cardiac function and cardiac structural changes and liver and kidney function. Results: At 24 weeks after treatment, heart function improved and ventricular remodeling reversal were statistically significant (P <0.05). Conclusion: Carvedilol can reverse ventricular remodeling and improve cardiac function in patients with acute myocardial infarction.