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目的分析剖宫产围手术期预防性应用抗菌药物的临床效果。方法以我院2014年1月~2014年10月择期剖宫产手术150例产妇为研究组,通过MTP(监测-培训-计划)模式预防性应用抗菌药物,选择2012年1月~2012年10月接受剖宫产手术的150例产妇为对照组,抗菌药物常规使用,比较两组预防性抗菌药物使用种类、用药时机、疗程、用药效果及不良反应。结果两组预防性抗菌药物使用时机及持续时间比较差异显著(P<0.01)。研究组无切口感染发生,与对照组的4.0%比较差异显著(P<0.05)。另外两组住院时间[(7.2±1.3)VS(8.8±1.5)]d比较差异显著(P<0.01)。结论根据MTP模式预防性应用抗菌药物合理性高,能有效预防或减少切口感染,缩短住院时间。
Objective To analyze the clinical effect of prophylactic antibacterials in cesarean section perioperative period. Methods A total of 150 maternal women scheduled for cesarean section from January 2014 to October 2014 in our hospital were enrolled in the study. Preventive antibacterials were administered through MTP (monitoring - training - planning) mode, and selected from January 2012 to October 2012 150 cases of cesarean section received monthly operation as control group. Antibacterials were routinely used. The types of preventive antibacterials used, the timing of treatment, the course of treatment, the effect of treatment and the adverse reactions were compared. Results The duration and duration of use of prophylactic antibiotics in both groups were significantly different (P <0.01). No incision infection occurred in the study group, which was significantly different from that of the control group (4.0%) (P <0.05). The other two groups of hospital stay [(7.2 ± 1.3) VS (8.8 ± 1.5)] d significant difference (P <0.01). Conclusion According to MTP model prophylactic use of antimicrobial agents reasonable, can effectively prevent or reduce incision infection, shorten the hospital stay.