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目的:在综合治疗的基础上,比较重型新生儿破伤风不同疗法的病死率并作死因分析。方法:分析了58例重型新生儿破伤风患儿,其中行早期气管插管组23例,晚期气管插管组24例,未行气管插管组11例。结果:由于注重了早期气管插管,新生儿重型破伤风患儿病死率由原来的588%下降到现在的83%,早期气管插管组病死率(43%)明显低于晚期气管插管组(500%),P<001;而未行气管插管组病死率最高(818%)。早期气管插管组没有因呼衰或窒息而死亡者。结论:早期气管插管不仅可降低重型新生儿破伤风的病死率,还可减少呼吸道并发症。
OBJECTIVE: To compare the mortality of different neonates with tetanus on the basis of comprehensive treatment and analyze the cause of death. Methods: 58 children with severe neonatal tetanus were analyzed, including 23 cases of early tracheal intubation group, 24 cases of late endotracheal intubation group and 11 cases of no endotracheal intubation group. Results: Due to the emphasis on early tracheal intubation, the mortality rate of neonatal tetanus in children dropped from 58.8% to 8.3%, and the mortality rate in early tracheal intubation group (4.3%) was significantly lower In the late endotracheal intubation group (50.0%), P <001; while the endotracheal intubation group had the highest case fatality rate (818%). Early tracheal intubation group did not death due to respiratory failure or asphyxia. Conclusion: Early tracheal intubation can not only reduce the mortality rate of heavy neonatal tetanus, but also reduce respiratory complications.