论文部分内容阅读
目的探讨微创经皮椎体成形术在控制脊柱转移性肿瘤围术期感染中的效果。方法选取2008年2月-2010年10月进行治疗的26例脊柱转移性肿瘤患者为研究对象,将其根据手术方式分为A组:开放式椎体后凸成形术组,B组:微创经皮椎体成形术组,每组各13例;将两组患者的感染发生率及手术前后的血清CRP、IL-6、IL-8及TNF-α水平进行统计及比较。结果感染发生率A组为23.1%、B组为0;B组术后1、3 d血清CRP为(27.86±6.34、13.24±4.68)mg/L,IL-6为(176.50±13.05、98.77±9.86)ng/L,IL-8为(298.64±23.56、156.41±25.60)ng/L,TNF-α为(23.24±4.01、15.09±3.50)ng/L;A组CRP(18.12±5.06、8.76±2.15)mg/L,IL-6为(113.02±12.45、72.37±10.87)ng/L,IL-8为(245.96±22.38、102.34±23.14)ng/L,TNF-α为(16.20±2.78、9.46±2.96)ng/L;B组水平均低于A组,差异有统计学意义(均P<0.05)。结论微创经皮椎体成形术,在控制脊柱转移性肿瘤围术期感染中的效果较好,优势明显。
Objective To investigate the effect of minimally invasive percutaneous vertebroplasty on perioperative infection of spine metastatic tumors. Methods Twenty-six patients with metastatic spine tumors treated from February 2008 to October 2010 were divided into group A (open kyphoplasty), group B (minimally invasive) Percutaneous vertebroplasty group, each group of 13 cases; the incidence of infection in both groups and before and after surgery serum levels of CRP, IL-6, IL-8 and TNF-α were statistically compared. Results The incidence of infection was 23.1% in group A and 0 in group B. The CRP levels in group B were (27.86 ± 6.34, 13.24 ± 4.68) mg / L and (176.50 ± 13.05, 98.77 ± 9.86 ± 0.06, and 36.61 ± 25.60 ng / L, respectively, and TNF-α was (23.24 ± 4.01,15.09 ± 3.50) ng / 2.15) mg / L, IL-6 was (113.02 ± 12.45,72.37 ± 10.87) ng / L, IL-8 was (245.96 ± 22.38,102.34 ± 23.14) ng / L and TNF-α was (16.20 ± 2.78,9.46 ± 2.96) ng / L; the level of B group was lower than that of A group (P <0.05). Conclusions Minimally invasive percutaneous vertebroplasty is more effective in controlling perioperative infection of spinal metastases and has obvious advantages.