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本文统计我院NICU中56例应用呼吸器治疗的新生儿中，发生呼碱15例，占26．8％。其中足月儿4／25例，早产儿11／31例，早产儿较足月儿更易发生，本文6例死亡亦为早产儿。在原发疾病中，以RDS最易出现，共8/17例，发生呼碱的时间，为呼吸器治疗后平均35.5小时。其原因可能与RDS病情恢复，不能及时判断肺顺应性变化，调整呼吸器参数；呼碱临床诊断困难，而血气分析监测不及时等因素有关。为预防呼碱的发生，作者认为，在呼吸器治疗期间，应定期监测血气、胸片并及时调整呼吸器参数，开展适用的监测技术，如PETCO2；及时了解PaCO2的变化，防止过度通气的发生。
In this paper, NICU in our hospital 56 cases of neonates treated with respirators, 15 cases of exhaled alkali, accounting for 26.8%. Among them, 4/25 full-term infants, 11/31 preterm infants, premature infants more likely to occur than full-term children, 6 cases of death in this paper also for premature children. In the primary disease, the most prone to RDS, a total of 8/17 cases, the time of exhalation, for the average 35.5 hours after respirator treatment. The reason may be related to the recovery of RDS, can not be timely to determine changes in lung compliance, adjust the respirator parameters; clinical diagnosis of Hypocapnia difficult, and blood gas analysis and monitoring is not timely and other factors. To prevent the occurrence of exhalation, the authors believe that during the respirator treatment, blood gas, chest X-ray should be regularly monitored and respiratory parameters adjusted to carry out appropriate monitoring techniques, such as PETCO2; PaCO2 changes in a timely manner to prevent the occurrence of hyperventilation .