A transgenic pig model expressing a CMV-ZsGreen1 reporter across an extensive array of tissues

• 作 者: Amy T.Desaulniers Rebecca A.Ce
• 机 构: DepartmentofAnimalScience,DepartmentofPharmacologyandExperimentalNeuroscience
• 出 处: 生物医学研究杂志:英文版
• 发表日期: 2021年2期
• 关键词: gene expression profiling CMV promoter ZsGreen1 biomedical model genome editing
• 基金项目: This project was partially supported by the Nebraska Agricultural Experiment Station with funding from the Hatch Multistate Research capacity funding program(Accession No.1011129 to BRW),an Agricultur

Since genetic engineering of pigs can benefit both biomedicine and agriculture,selecting a suitable gene promoter is critically important.The cytomegalovirus(CMV)promoter,which can robustly drive ubiquitous transgene expression,is commonly used at present