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目的探讨慢性前列腺炎前列腺液细菌学检测的临床意义。方法对261例慢性前列腺炎患者作前列腺液细菌培养、药敏试验及D-实验。结果261例前列腺液中分离出200株细菌,分离率73.6%。溶血葡萄球菌占总检出率的36.5%,未见对万古霉素、替考拉宁耐药菌株,复方新诺明、利福平、呋喃妥因有相当好的抗菌活性,对其他抗生素都呈不同程度的耐药,其中红霉素诱导型克林霉素占较高的比例,对苯唑西林耐药率高达94.3%。结论多重耐药及高耐药机制十分复杂的溶血葡萄球菌已成为引起慢性前列腺炎最常见的致病菌,给临床医生提供正确的病原学诊断和药敏结果是治疗慢性前列腺炎科学的依据。
Objective To investigate the clinical significance of bacteriological examination of prostatic fluid in patients with chronic prostatitis. Methods 261 cases of chronic prostatitis in patients with prostatic fluid bacterial culture, drug sensitivity test and D-experiment. Results 200 strains of bacteria were isolated from 261 cases of prostatic fluid with a separation rate of 73.6%. Staphylococcus aureus accounted for 36.5% of the total detection rate, no vancomycin, teicoplanin resistant strains, cotrimoxazole, rifampicin, nitrofurantoin have quite good antibacterial activity, were different for other antibiotics Degree of resistance, including erythromycin inducible clindamycin accounted for a higher proportion of oxacillin resistance rate as high as 94.3%. Conclusions Staphylococcus aureus, which has a complex mechanism of multi-drug resistance and high resistance, has become the most common causative agent of chronic prostatitis. It is of great help to clinicians to provide correct etiological diagnosis and drug susceptibility results for the treatment of chronic prostatitis.