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冠脉支架载有洗脱药物对经皮冠状动脉介入治疗(PCI)术后再狭窄的预防起重要作用。近期临床研究报道显示,载有雷帕霉素药物的支架使PCI术后再狭窄率从15%～30%降至0。此项研究的目的是观察Zotarolimus药物作用机制及其在体外和体内实验中的有效性,Zotaroli mus是免疫抑制剂雷帕
Coronary stents carry eluting agents that play an important role in the prevention of postoperative restenosis after percutaneous coronary intervention (PCI). Recent clinical studies have shown that rapamycin-loaded stents reduced the rate of restenosis after PCI from 15% to 30%. The purpose of this study was to investigate the mechanism of action of Zotarolimus drugs and their effectiveness in vitro and in vivo experiments. Zotaroli mus is an immunosuppressant Rapa