决明子降低血清胆固醇机制的探讨

• 作 者: 何菊英 刘松青 陈泽莲 唐敏
• 机 构: Department of Pharmacy, Southwest Hospital,Third Military Medical University, Third Military Medical
• 出 处: 中国临床康复
• 发表日期: 2003年3期
• 关键词: plants medicinal hepatocytes/chemistyr cholesterol/blood scintillation counting/

AIM: To investigate mechanism of cassia obtusifolia reducing terol.METHODS: Liver cell of the rats were cultured in vitro.14C-cholesterol synthesized in liver cells wers measured with Lowry methodand scintillation counting apparatus.RESULTS:Extract of cassia obtusifoliacaninhibit synthesis of 14C-cholesterol but Cassiaside B didnt affectcholesterol syntbesis.CONCLUSION: One of the mechanism of cassia ob-tusifolia reducing blood cholesterol is nihibiting synthesis of cholesterol tosome extent,while casiaside B reducing is not by inhibiting synthesis of cholesterol.