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调查医院感染菌及其耐药性的动态变化。Ｇ－球菌所占的年比例从１９９１、１９９２年的５３．６％和５１．５％上升至１９９３年的６２．３％，Ｇ＋球菌呈下降趋势。金黄色葡萄球菌对青霉素的耐药率已＞９０％。各常见菌对头孢菌素类药物的耐药率呈持续上升趋势，３年间铜绿假单胞菌、表皮葡萄球菌、不动杆菌、阴沟肠杆菌对庆大霉素的耐药率上升均超过２０％，对丁胺卡那的耐药率呈下降趋势。氨苄青霉素经限用后其使用率由８４％降至２．９％，金黄色葡萄球菌、Ｄ群肠球菌、阴沟肠杆菌等对其耐药率均呈下降趋势。
To investigate the dynamic changes of nosocomial infections and drug resistance in hospital. The annual proportion of G-cocci increased from 53.6% and 51.5% in 1991 and 1992 to 62.3% in 1993, and the G + cocci showed a decreasing trend. Staphylococcus aureus penicillin resistance rate has been> 90%. The rates of resistance to cephalosporins in all common bacteria showed an upward trend. The rates of resistance to gentamicin of Pseudomonas aeruginosa, Staphylococcus epidermidis, Acinetobacter, and Enterobacter cloacae increased more than 20 %, The rate of resistance to amikacin decreased. After limited use of ampicillin, its use rate was reduced from 84% to 2.9%. Staphylococcus aureus, Group D enterococci, Enterobacter cloacae, etc. showed a downward trend in resistance rate.