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目的：探讨急性氟乙酰胺中毒的临床特征与诊治。方法：分析近2年经法医验证后确诊的46例急性中毒致死者病例。结果：显示口服重度急性中毒者起病急骤，症状以恶心、呕吐、胸骨后或上腹痛、头晕、抽搐、尖叫及心跳骤停为突出表现。尸检证实病变最严重的脏器依次为心、脑、肺、肝、肾等。结论：用硫靛反应（层析法）从生物和非生物检材中，检出有氟乙酰胺的代谢物氟乙酸存在，为确诊急性氟乙酰胺中毒的敏感而可靠的方法。误服后2～3h洗胃效果甚微，乙酰胺为首选的救治药物。
Objective: To investigate the clinical features and diagnosis and treatment of acute fluoroacetamide poisoning. Methods: Analysis of nearly 2 years confirmed by forensic medical confirmed 46 cases of acute poisoning. Results: The patients with acute severe oral poisoning showed a sudden onset of symptoms characterized by nausea, vomiting, post-sternal or upper abdominal pain, dizziness, convulsions, screaming and sudden cardiac arrest. Autopsy confirmed lesions of the most serious organs followed by heart, brain, lung, liver, kidney and so on. CONCLUSIONS: The presence of fluoroacetic acid, a metabolite of fluoroacetamide, was detected in both biological and non-biological samples by thioindigo reaction (chromatography), a sensitive and reliable method for the diagnosis of acute fluoroacetamide intoxication. 2 ~ 3h after oral administration of gastric lavage effect is minimal, acetamide is the preferred treatment drug.