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目的分析血液灌流在重症药物中毒患者中应用的临床效果,总结急救经验,提高医疗质量。方法选择138例重症药物中毒患者分为实验组和对照组各69例。实验组在内科常规治疗的基础上,同时给予血液灌流治疗,对照组只采用内科传统方法常规治疗。观察记录两组患者意识恢复的时间、胆碱酯酶活力恢复时间与阿托品用量、平均住院天数、死亡率和中间合并症、心肌酶和肝功能恢复时间等情况。结果实验组比对照组意识恢复的时间明显缩短,胆碱脂酶活力恢复时间缩短,阿托品用量减少,患者住院天数缩短,死亡率和中间合并症降低,心肌酶和肝功能恢复时间缩短,两组相比较差异有统计学意义(P<0.05)。结论重症药物中毒患者应用血液灌流急救疗效显著,提高了重症药物中毒患者治愈率,促进了患者康复,值得临床应用。
Objective To analyze the clinical effect of hemoperfusion in patients with severe drug poisoning, summarize the experience of first aid and improve the quality of medical care. Methods Select 138 cases of severe drug poisoning patients divided into experimental group and control group of 69 cases. The experimental group was treated with hemoperfusion on the basis of routine medical treatment, while the control group was treated by traditional medical methods only. The patients’ recovery time, the recovery time of cholinesterase and the dosage of atropine, the average days of hospitalization, mortality and intermediate complications, the time of recovery of myocardial enzymes and liver function were observed and recorded. Results Compared with the control group, the time to recovery of consciousness was shortened, the recovery time of cholinesterase activity was shortened, the dosage of atropine was decreased, the length of hospital stay was shortened, the mortality and intermediate complications were decreased, and the time for recovery of myocardial enzymes and liver function was shortened. Compared with the difference was statistically significant (P <0.05). Conclusion Severe drug poisoning patients with hematuria emergency treatment efficacy is significant, increased the cure rate of patients with severe drug poisoning, and promote the rehabilitation of patients, it is worth clinical application.