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对24例慢性肾小球肾炎患者红细胞C3b受体花环率和红细胞免疫复合物花环率检测结果进行分析。结果表明:慢性肾炎患者红细胞C3b受体花环率明显降低,与对照组比较有显著差异(P<0.01),红细胞免疫复合物花环率与对照组相比无显著差异(P>0.05)。慢性肾炎尿毒症组红细胞C3b受体花环率低于肾功能正常组,两组有显著差异(P<0.05),且与血肌酐浓度呈负相关(r=-0.4095)。结果提示红细胞免疫功能低下,可能是肾小球肾炎发病过程中的重要因素之一,并且可以作为了解患者病情和判断预后的参考指标。
The results of analysis of rosette C3b receptor rosette rate and erythrocyte immune complex rosette rate in 24 patients with chronic glomerulonephritis were analyzed. The results showed that the rosette of erythrocyte C3b receptor in patients with chronic nephritis was significantly lower than that in the control group (P <0.01), and there was no significant difference in the rate of rosette of erythrocyte immune complex compared with the control group (P> 0.05 ). There was a significant difference between the two groups (P <0.05) and a negative correlation (r = -0.4095) with the serum creatinine concentration in the chronic nephritis uremia group. The results suggest that red cell immune dysfunction may be one of the important factors in the pathogenesis of glomerulonephritis, and can be used as a reference to understand the patient’s condition and prognosis.