Continuous release of interleukin 12 from microencapsulated engineered cells for colon cancer therap

• 作 者: ShuZheng Zuo-XiangXiao Yue-Lon
• 机 构: CancerInstitute
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2003年5期
• 关键词: 微胶囊化工程细胞 白细胞介素-12 结肠癌 肿瘤治疗学 肿瘤抑制 细胞因子
• 基金项目: 国家自然科学基金

AIM: To explore the anti-tumor immunity against CT26 colon tumor of the microencapsulated cells modified with murine interleukine-12 (mIL-12) gene.METHODS: Mouse fibroblasts (NIH3T3) were stably transfected to express mIL-12 using expression plasmids carr