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本文报告测定亚临床糖尿病患者随机尿标本中总蛋白及N-乙酰-β-氨基葡糖苷的结果及其临床意义。 研究对象为在过去6个月～1年间试纸法检查随机尿蛋白5次阴性的糖尿病患者(阴性群)和出现1次以上假阳性的患者(间歇阳性群)30名,并以无肾脏疾患、糖尿病、高血压等病史随机尿试验法检查糖、蛋白、隐血反应阴性的134名正常人为对象。给研究对象测定随机尿总蛋白、肌酐和N-乙酰-β-D-氨基葡糖苷酶(NAG)活性,用改良的微量比浊法测定尿总蛋白。测定结果分别以蛋白/肌酐和NAG/肌酐作为蛋白指数和NAG指数表示。
This paper reports the determination of total protein and N-acetyl-β-glucosaminoglycans in random urine samples from patients with subclinical diabetes mellitus and its clinical significance. Participants were 30 diabetic patients (negative group) and 30 patients (more than one intermittent positive group) with negative urine protein 5 times in the past 6 months to 1 year by the test strip method, and had no kidney disease, Diabetes, hypertension and other history of random urine test to check the sugar, protein, occult blood test negative 134 normal subjects. Urine total protein, creatinine, and N-acetyl-β-D-glucosaminidase (NAG) activity were measured in all subjects. Total urinary total protein was determined by modified microtitration method. The results were expressed as protein / creatinine and NAG / creatinine as protein index and NAG index, respectively.