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目的探讨米非司酮配伍雷夫诺尔在瘢痕子宫中期妊娠引产的效果。方法选取要求终止中期妊娠孕妇133例(孕14~28周),其中瘢痕子宫妊娠孕妇59例(瘢痕组),非瘢痕子宫妊娠孕妇74例(对照组),采用米非司酮配伍雷夫诺尔经腹羊膜腔内注射引产。观察两组引产结局。结果瘢痕组59例中,引产成功56例,引产术中出血过多而中转子宫动脉栓塞治疗2例(1例出血2500ml,另1例出血1050ml);引产术后24h宫缩未发动遂进行二次雷夫诺尔引产1例;人工剥离胎盘19例。对照组74例均引产成功,胎盘均自然娩出。两组均未发生产后感染、羊水栓塞和子宫破裂。结论米非司酮配伍雷夫诺尔经腹羊膜腔内注射用于瘢痕子宫中期妊娠引产可以提高引产成功率。
Objective To investigate the efficacy of mifepristone in combination with Levonorole in the induction of labor in the second trimester of uterine scar. METHODS: A total of 133 pregnant women of the second trimester were enrolled in this study. Fifty-nine pregnant women with scar uterine pregnancy (scar group) and 74 pregnant women with non-scarring uterus (control group) were enrolled. Mifepristone Transabdominal injection of induced abortion. Observation of two groups induced abortion. Results 59 cases of scar group, 56 cases of successful induction of labor, induced abortion and uterine artery embolization in 2 cases (1 case of bleeding 2500ml, another case of bleeding 1050ml); induced abortion 24h after uterine contractions did not start then Lesque Nuer abortion in 1 case; 19 cases of manual dissection of the placenta. 74 cases of control group were successful abortion, the placenta are delivered naturally. Postpartum infection, amniotic fluid embolism and uterine rupture did not occur in either group. Conclusion The combination of mifepristone and lefloxacin intra-abdominally intra-peritoneal injection of abortion for uterine scar pregnancy can increase the success rate of induction of labor.