Advances in drug delivery system for platinum agents based combination therapy

• 作 者: Xiang Kang Hai-Hua Xiao Hai-Qi
• 机 构: DepartmentofObstetricsandGynecology,StateKeyLaboratoryofPolymerPhysicsandChemistry,UniversityofChine
• 出 处: 癌症生物学与医学：英文版
• 发表日期: 2015年4期
• 关键词: 治疗药物 基础 传递系统 铂 抗癌药物 药物开发 纳米技术 药物疗效 Cancer drug delivery combination therapy plat
• 基金项目: supported by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaAcknowledgements This work was supported by Union Hospital, Tongji Medical College, Huaz

Platinum-based anticancer agents are widely used as first-line drugs in cancer chemotherapy for various solid tumors. However, great side effects and occurrence of resistance remain as the major drawbacks for almost all the platinum drugs developed. To co