胃十二指肠疾病患者骨矿物质含量的变化意义

• 作 者: 王颖 叶一秀 徐冰
• 出 处: 新消化病学杂志
• 发表日期: 1997年04期
• 关键词: 骨矿物质含量 胃肿瘤 骨矿含量 骨密度 慢性萎缩性胃炎 胃炎／代谢 消化性溃疡 慢性胃炎 胃十二指肠疾病 单光子吸收

目的研究慢性胃炎、胃十二指肠溃疡和胃癌患者骨矿物质含量变化的意义．方法用单光子吸收法，以桡骨长度中下１／３处为测定点，测定慢性胃炎（ｎ＝３１）、消化性溃疡（ｎ＝２６）、胃癌（ｎ＝９）及正常对照组（ｎ＝４３）的骨矿物质含量，并以骨矿含量（ＢＭＣ，ｇ／ｃｍ）及骨面密度（ＢＭＣ／ＢＷ，ｇ／ｃｍ２）表示，并进行比较．结果慢性萎缩性胃炎（ｎ＝１４），ＢＭＣ＝１００８±０２２８ｇ／ｃｍ）和十二指肠球部溃疡（ｎ＝１６），ＢＭＣ＝０９０４ｇ／ｃｍ±０２０５ｇ／ｃｍ，ＢＭＣ／ＢＷ＝０６５２ｇ／ｃｍ２±００８６ｇ／ｃｍ２）骨矿含量显著低于正常对照组（ｎ＝４３，ＢＭＣ＝１１７６ｇ／ｃｍ±０３４１ｇ／ｃｍ，ＢＭＣ／ＢＷ＝０７８２ｇ／ｃｍ２±０１３４ｇ／ｃｍ２，Ｐ＜００５）．结论萎缩性胃炎及十二指肠溃疡患者ＢＭＣ明显下降，需纠正．

Objective To study the significance of changes in bone mineral content in patients with chronic gastritis, gastroduodenal ulcer and gastric cancer. Methods Single photon absorption method was used to determine the chronic gastritis (n=31), peptic ulcer (n=26), gastric cancer (n=9) and normal control group (n=1). Bone Mineral Content = 43), expressed as bone mineral content (BMC, g/cm) and bone surface density (BMC/BW, g/cm2), and compared. Results Chronic atrophic gastritis (n=14), BMC=1008±0228g/cm) and duodenal ulcer (n=16), BMC=0904g/cm±0205g/cm BMC/BW=0652g/cm2±0086g/cm2) bone mineral content was significantly lower than normal control group (n=43, BMC=1176g/cm±0341g/cm, BMC/BW=0 782g/cm2±0134g/cm2, P<005). 2. Conclusion BMC in patients with atrophic gastritis and duodenal ulcer is obviously decreased and needs to be corrected.