【摘 要】
：
目的:研究黄芪、灵芝、茯苓、党参、当归、天花粉等中药多糖对红细胞膜相CD35免疫活性的调节作用.方法:采用10%CD35单克隆抗体阻断试验,比较以上中药多糖在10%CD35单克隆抗体
【机 构】
：
陕西省人民医院免疫研究室,西安,710068
论文部分内容阅读
目的:研究黄芪、灵芝、茯苓、党参、当归、天花粉等中药多糖对红细胞膜相CD35免疫活性的调节作用.方法:采用10%CD35单克隆抗体阻断试验,比较以上中药多糖在10%CD35单克隆抗体阻断前后红细胞膜相CD35活性的变化.结果:40例健康献血员和30例恶性肿瘤患者的红细胞经以上中药多糖作用后,其RBC.C3bRR与对照组相比明显提高(P＜0.01).用10%CD35单克隆抗体阻断恶性肿瘤患者的红细胞膜相CD35后,其RBC.C3bRR明显下降(P＜0.01).用以上中药多糖作用过的补体致敏酵母菌作红细胞RBC.3bRR试验,其花环率无明显变化(P＞0.05),而将以上中药多糖作用过的红细胞作红细胞RBC.C3bRR试验,其花环率明显升高(P＜0.01).结论:研究说明以上中药多糖能增强健康献血员和恶性肿瘤患者的红细胞免疫功能,并提示以上中药多糖调节红细胞膜相CD35免疫活性的机制,与补体致敏酵母菌无关,而与红细胞膜相CD35活性有关.
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