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目的观察硫酸镁联合拉贝洛尔治疗中重度妊高征的临床疗效。方法将2009年7月-2012年10月我科收治的81例中重度妊高征患者随机分为对照组与观察组,除外常规治疗,对照组应用硫酸镁,观察组在对照组基础上加用拉贝洛尔,记录并作回顾性分析。结果治疗后观察组的平均动脉压、24 h尿蛋白量以及胎心异常发生率均明显低于对照组,且差异具有统计学意义(P<0.05)。结论硫酸镁联合拉贝洛尔治疗中重度妊高征的临床疗效确切,能够显著改善患者的临床症状及体征,对胎心较小,值得临床上进一步研究推广。
Objective To observe the clinical efficacy of magnesium sulfate combined with labetalol in the treatment of moderate and severe pregnancy-induced hypertension. Methods From July 2009 to October 2012, 81 patients with moderate-to-severe pregnancy-induced hypertension in our department were randomly divided into control group and observation group, except for conventional treatment. The control group was given magnesium sulfate. The observation group was added on the basis of the control group Labetalol, recorded and retrospectively analyzed. Results After treatment, mean arterial pressure, 24-hour urinary protein, and fetal heart rate in the observation group were significantly lower than those in the control group, and the difference was statistically significant (P <0.05). Conclusion Magnesium sulfate combined with labetalol in the treatment of moderate and severe pregnancy-induced hypertension clinical curative effect is exact, can significantly improve the patient’s clinical symptoms and signs of fetal heart rate is small, it is worth further study in clinical promotion.