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目的:探讨急性病毒性脑炎患儿的视觉通路受累程度和性质。方法:对30例急性病毒性脑炎患者(年龄5~12岁),疾病最初显现的12d内视觉诱发电位(VEP)进行调查。在急性病毒性脑炎患者和水痘蜱传脑炎患者之间比较P100峰潜伏期及振幅。结果:两种形式脑炎患儿之间无显着差异。研究对象组中,40%的患者表现出视觉皮层功能障碍(P100振幅降低),沿视觉通路(P100潜伏期延长)电导率温和放缓的迹象。结论:研究发现,视觉通路对病毒性脑炎有很强的耐受性。功能性视皮层对该疾病的抵抗力低。
Objective: To investigate the extent and nature of visual pathway involvement in children with acute viral encephalitis. Methods: The visual evoked potential (VEP) in 30 patients with acute viral encephalitis (aged 5 to 12 years) and the disease first appeared within 12 days were investigated. P100 peak latency and amplitude were compared between patients with acute viral encephalitis and tick-borne encephalitis. Results: There was no significant difference between children with both forms of encephalitis. In the study cohort, 40% of patients showed signs of mildly reduced conductance in the visual cortex (decreased P100 amplitude) and along the visual pathway (prolonged P100 latency). Conclusion: The study found that visual access to viral encephalitis is well tolerated. Functional visual cortex resistance to the disease is low.