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目的探讨急性缺血性卒中与血清超敏C反应蛋白(hs蛳CRP)的关系。方法对155例经头颅CT或MRI证实的急性缺血性卒中患者于发病3d内采用比浊法测定hs蛳CRP,根据hs蛳CRP的结果分组。结果梗死病灶大的患者血清hs蛳CRP水平明显高于梗死病灶比较小的患者(P<0.05),有脑卒中病史的患者血清hs蛳CRP的水平高于无脑卒中病史的患者(P<0.05)。结论在卒中和动脉硬化的病因学中炎症反应起重要作用,在卒中的处理中还需要进一步采取干预炎症反应的治疗。
Objective To investigate the relationship between acute ischemic stroke and serum high sensitivity C reactive protein (hs 蛳 CRP). Methods 155 cases of acute ischemic stroke confirmed by skull CT or MRI were examined by turbidimetric method for the determination of hs 蛳 CRP within 3 days of onset, and were grouped according to the results of hs 蛳 CRP. Results Serum hs-CRP level was significantly higher in patients with large infarction than in patients with smaller infarction (P <0.05). The serum levels of hs-CRP in those with history of stroke were higher than those without history of stroke ). Conclusion Inflammatory reactions play an important role in the pathogenesis of stroke and atherosclerosis. In the treatment of stroke, further intervention in the treatment of inflammatory reactions is needed.