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目的 探讨先天性唇、腭裂对患儿呼吸系统顺应性 (CT)的影响。方法 唇裂或腭裂病儿 2 40例 (观察组 ) ,非唇腭裂病儿 6 0例 (对照组 )均为择期手术患者 ,按年龄段 :1~ 12月、1~ 3岁、4~ 7岁、8~ 12岁 ,各分为 5个亚组。全麻诱导气管内插管后 ,行机械通气 ,保持PETCO2 4~ 4.6kPa ,用DatexUltima监测仪测定CT。结果 与非唇裂同一年龄组CT 值相比 ,唇裂各年龄组、腭裂 1~ 12月及 1~ 3岁组CT 值无显著性差异 ,而腭裂 4~ 7岁、8~ 12岁组明显下降 (P <0 .0 1)。非唇腭裂和唇裂各年龄组比顺应性值组间比较无显著性差异 ,与腭裂 1~ 12月组相比 ,腭裂 4~ 7岁、8~ 12岁组显著下降 (P <0 .0 1)。结论 先天性腭裂患儿 ,随年龄增长 ,CT 进一步下降 ,因而腭裂修复术宜早期进行。
Objective To investigate the effect of congenital lip and cleft palate on respiratory compliance (CT) in children. Methods Forty-two children with cleft lip or cleft palate (observation group) and 60 non-cleft lip and palate children (control group) underwent elective surgery. The patients were divided into three groups according to age group: 1-12 months, 1-3 years old, 4-7 years , 8 to 12 years old, divided into 5 subgroups. After induction of anesthesia endotracheal intubation, mechanical ventilation, maintaining PETCO2 4 ~ 4.6kPa, measured with a DatexUltima monitor CT. Results Compared with non-cleft lip in the same age group CT values, cleft lip in all age groups, cleft palate 1 to 12 months and 1 to 3 years old group CT value was no significant difference, and cleft palate 4 to 7 years old, 8 to 12 years old group decreased significantly P <0 .0 1). There was no significant difference between the cleft palate and cleft lip in each age group compared with the compliance group. Cleft palate was significantly lower in 4-7 years old group and 8-12 years old group than in cleft palate 1-12 month group (P <0.01) ). Conclusion Children with congenital cleft palate, with age, CT decreased further, so cleft palate repair should be carried out early.