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目的 对口腔癌患者血清TPS水平进行研究 方法 对39例口腔癌患者的血清特异性组织多肽抗原(TPS)浓度进行了检测。结果 癌症组血清TPS浓度明显高于健康对照组(P<0.001)。口腔癌阳性检出率达79.4％,其中唾液腺癌70.6％,舌癌85.7％,唇、颊癌75％。随着病程发展,血清TPS浓度呈升高趋势。结论 血清TPS对口腔癌阳性检出率较高,并与淋巴结转移及临床分期关系密切,血清TPS水平越高,预后愈差。
Objective To investigate the serum TPS level in oral cancer patients and to detect the concentration of serum specific antigenic peptide (TPS) in 39 cases of oral cancer patients. Results The serum TPS level in cancer group was significantly higher than that in healthy control group (P <0.001). The positive rate of oral cancer was 79.4%, of which salivary gland carcinoma was 70.6%, tongue carcinoma 85.7%, lip and cheek carcinoma 75%. With the progression of the disease, serum TPS concentrations showed an upward trend. Conclusion The positive rate of TPS in oral cancer is high, which is closely related to the lymph node metastasis and clinical stage. The higher the serum TPS level, the worse the prognosis.