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Ⅰ型超敏反应能干挠Ⅳ型免疫反应的产生,而对皮肤霉菌抗原的特发性反应总是伴有对于感染性霉菌的、较低的迟发性皮肤反应。作者提出的一例皮肤粘膜念珠菌病的报告,证实了另一种速发型与迟发型免疫系统相互作用的临床结果,在接触局部的食物过敏原后,口腔念珠菌病恶化了。患者16岁,女性。从两岁起开始患指甲念珠菌病,8岁患甲状腺功能低下,11岁时念珠菌病罹及颊粘膜、甲沟、及面部皮肤。从12岁起至14岁零九个月止,曾间断接受转移因子治疗,间或与二性霉素B配伍应用。
Type I hypersensitivity reacts to type IV immune responses, whereas idiopathic reactions to dermal mold antigens are always accompanied by a lower delayed skin reaction to infectious molds. The authors report of a case of cutaneous mucocutaneous candidiasis confirms another clinical result of an interaction between immediate and delayed immune systems that worsens oral candidiasis following exposure to local food allergens. Patient 16 years old, female. From the age of two began suffering from fingernail candidiasis, 8-year-old suffering from hypothyroidism, 11 years old, candidiasis and buccal mucosa, a ditch, and facial skin. From the age of 12 to 14 years and nine months, it has been intermittently accepted transfer factor treatment, or with amphotericin B compatibility applications.