论文部分内容阅读
胃肠间质瘤(gastrointestinal stromal tumors,GIST)被认为起源于间质Cajal细胞,可发生于胃、小肠、直肠、肠系膜及大网膜,是具有恶性潜能的肿瘤。高危型GIST患者术后复发转移率高,主要有局部复发、腹腔种植和肝转移,个别病例也可发生肺转移[1],但其他部位转移极为少见。本文报道1例胃肠间质瘤颅骨转移,结合文献讨论其临床病理学特点。1临床资料患者女性,71岁。4年前曾行小肠间质瘤切除术。术后病理诊断:小肠高度危险性胃肠间质瘤,手术切缘阴性。术后未接受伊马替尼的药物治疗。1
Gastrointestinal stromal tumors (GISTs) are thought to originate from interstitial Cajal cells and can occur in the stomach, small intestine, rectum, mesentery and omentum and are malignant tumors. Patients with high-risk GIST have a high rate of postoperative recurrence and metastasis, mainly with local recurrence, peritoneal implantation and liver metastases, and pulmonary metastases in some cases [1], but rare metastasis elsewhere. This article reports a case of gastrointestinal stromal tumor skull metastasis, combined with the literature discuss its clinical and pathological features. 1 clinical data patients female, 71 years old. Intestinal stromal tumor resection 4 years ago. Postoperative pathological diagnosis: high risk of small intestinal gastrointestinal stromal tumors, negative surgical margins. No postoperative imatinib drug treatment. 1