Morphological observations of tumors in cardiac conduction system

来源 :Journal of Geriatric Cardiology | 被引量 : 0次 | 上传用户:liubin523
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Tumors of the cardiac conduction system(CCS) have rarely been reported. The CCS from 198 cardiac-related deaths(Group Ⅰ) ,and 838 deaths from non-cardiovascular diseases or trauma(Group Ⅱ) ,were studied. Sampling was done of the sinoatrial node(SAN) and atrio-ventricular node(AVN) along their long axis of each node as a single block and the His bundle(HB) perpendicular to its long axis in 2-4 blocks. Five-micron serial sections were made;tissue slices were taken intermittently,every 20th from the SAN,every 10th from the AVN,and every 30th from the HB and bundle branches(BB) ,by continuous slices three times. Tumors in the CCS were found in 12 cases(1.155 %) ,where 10(0.965%) were primary tumors,and 2(0.193%) were metastatic tumors. The primary tumors included 4 fibromata compressing the HB(0.386 %) ,4 hemangiomata(0.386%) ,1 AVN tumor(0.097 %) ,and 1 rhabdomyoma(0.097 %) . In 8 of the 10 cases,the tumors were located in the AVN or HB. The metastatic tumors originated from lymphocytic leukemia and malignant lymphoma(histiocytic type) in lung,and were all found in the SAN. Of the 12 cases,2 were from the group Ⅰ. Tumors in the CCS are the smallest tumors in different parts of the body,which can cause sudden death. The CCS from 198 cardiac-related deaths (Group I), and 838 deaths from non-cardiovascular diseases or trauma (Group II), were studied. Sampling was done of the Five-micron serial sections were made along their long axis of each node as a single block and the His bundle (HB) perpendicular to its long axis in 2-4 blocks. Tissues were taken intermittently, every 20th from the SAN, every 10th from the AVN, and every 30th from the HB and bundle branches (BB), by continuous slices three times. Tumors in the CCS were found in 12 cases (1.155%) , the first tumors included 4 fibromata compressing the HB (0.386%), 4 hemangiomata (0.386%), 1 AVN tumor (0.097%), and 1 rhabdomyoma (0.097%). In 8 of the 10 cases, the tumors were located in the AVN or HB. The metastatic tumors originated from lymphocyt Of the 12 cases, 2 were from the group I. Tumors in the CCS are the smallest tumors in different parts of the body, which can cause sudden death
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