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目的：了解纤维支气管镜（FB）检查对原因不明外周孤立性肺球形病灶诊断价值。方法：将原因不明孤立性外周肺结节（SPN）106例和孤立性外周肺块影（SPM）202例按FB检查结果、胸片、临床表现等，分为不同的亚组以了解影响FB检查结果的因素。结果：约57．5％经FB确诊为肺癌。SPN经FB肺癌诊断率与患者的年龄、病程、及咯血症状的有无等有关。而SPM经FB肺癌的诊断率仅与肿块的大小有关。约2．8％SPN和2．5％SPM在FB下病变超出一侧主支气管，另约1％SPN和8．4％SPM在FB下病变累及一侧主支气管。FB检查结果正常76例中，14．5％经刷检或盲式肺活检确诊为肺癌。结论：FB检查对原因不明外周孤立性肺球形病灶的诊断与分期具有较高的价值。
OBJECTIVE: To determine the value of fiberoptic bronchoscopy (FB) in the diagnosis of solitary pulmonary spherical lesions of unknown cause. METHODS: One hundred and sixty patients with unexplained isolated peripheral pulmonary nodules (SPN) and 202 patients with isolated peripheral lung mass shadow (SPM) were divided into different subgroups to understand the effect of FB according to FB test results, chest radiographs, and clinical manifestations. Check the results of the factors. Results: About 57.5% were diagnosed with lung cancer by FB. The diagnosis rate of SPN by FB lung cancer is related to the age, course of the disease, and the presence or absence of hemoptysis. The diagnosis rate of SPM by FB lung cancer is only related to the size of the tumor. About 2.8% of SPNs and 2.5% of SPM were lesioned beyond one side of the main bronchus under FB, and about 1% of SPN and 8.4% of SPM were involved in one side of the main bronchus under FB lesions. FB examination results were normal in 76 cases, 14.5% were diagnosed with lung cancer by brushing or blind lung biopsy. Conclusion: FB examination has high value for the diagnosis and staging of solitary pulmonary spherical lesions with unknown causes.