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1大肠腺瘤与癌早期病变的新观念大肠癌的发生、发展是多基因参与,多阶段、多步骤的过程,涉及到进行性的分子遗传学改变和相关的组织形态学改变,这个过程短则几年,长则十几年。就大肠癌来说,从正常黏膜到肉眼可见的腺瘤性息肉形成约需5～20年,从肿瘤到浸润性癌形成约需5～15年[1
A new concept of colorectal adenoma and early stage of cancer The occurrence and development of colorectal cancer is a multi-gene involved, multi-stage and multi-step process involving the progress of molecular genetic changes and related histopathological changes, this process is short A few years, long ten years. In colorectal cancer, the formation of adenomatous polyps visible from the normal mucosa to the naked eye takes about 5 to 20 years and takes approximately 5 to 15 years from tumor to invasive cancer [1