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目的探讨笑气用于分娩镇痛的安全性。方法将300例产妇随机分为观察组和对照组,对照组除不给予笑气外,其他的产科处理措施与观察组相同。观察两组的分娩阵痛效果、产程时间、分娩方式、新生儿Apgar评分、产后出血量、母体动脉血气分析,吸入笑气的不良反应等。结果观察组的阵痛强度评分明显低于对照组(P<0.001),总产程和活跃期均短于对照组,(P<0.05)差异有显著意义,而母体动脉血气分析、新生儿Apgar评分、产后出血量、分娩方式、吸入笑气不良反应均无统计学差异。结论笑气用于分娩镇痛是安全的。
Objective To investigate the safety of nitrous oxide in labor analgesia. Methods 300 pregnant women were randomly divided into observation group and control group. The control group was given the same obstetric treatment except for not giving noxiousness. Labor pain, labor duration, mode of delivery, neonatal Apgar score, postpartum hemorrhage, maternal arterial blood gas analysis and adverse reactions of inhalation of nitrous oxide were observed. Results The pain intensity of the observation group was significantly lower than that of the control group (P <0.001), and the duration of active labor and the duration of labor were shorter than those of the control group (P <0.05). However, the differences of maternal arterial blood gas analysis, Apgar score, Postpartum hemorrhage, mode of delivery, adverse reactions to inhalation of nitrous oxide were not statistically different. Conclusions Nausea is safe for labor analgesia.