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观察176例慢性阻塞性肺病(COPD)不同临床分期的动脉血气分析资料在动脉血气图上的变化规律.结果显示:(1)急性发作期患者的动脉血气分布在通气不足合并换气损害区(5区)占52.8 %、通气代偿换气损害区(4区)占25.6 %和通气过度合并换气损害区(6区)占21.6%.5区病例的病死率最高,为23.7%,高于4区和6区(P<0.05).(2)出院时(临床缓解期)96例复查血气,4区58例,占60.4%,5区26例,占27.1%,6区9例,占9.4%,血气正常区(1区)3例,占3.1%,其中92例动脉氧分压大于8.0kPa.(3)死亡者死亡前血气均在5区.动脉血气图可直观反映COPD患者通气和/或换气功能的病理生理变化,为临床分期、治疗方法选择和预后判断提供帮助.
The arterial blood gas analysis data of 176 cases with chronic obstructive pulmonary disease (COPD) in different clinical stages were observed and analyzed.The results showed that: (1) The arterial blood gas distribution in patients with acute exacerbation was significantly different (District 5) accounted for 52.8%, ventilatory compensatory ventilation damaged area (Area 4) accounted for 25.6% and hyperventilation combined ventilation damage area (Area 6) accounted for 21.6% .5 District cases the highest case fatality rate was 23.7%, high (4) and 6 (P <0.05). (2) At the time of discharge (clinical remission), 96 cases were examined blood gas, 58 cases in 4 districts, accounting for 60.4%, 26 cases in 5 districts, accounting for 27.1%, 9 cases in 6 districts, Accounting for 9.4%, 3 cases of normal blood gas (area 1), accounting for 3.1%, of which 92 cases of arterial oxygen pressure greater than 8.0kPa. (3) Before death, the blood gas are in zone 5. Arterial blood gas chart can be directly reflected COPD patients Ventilation and / or ventilatory function of the pathophysiological changes for clinical staging, treatment options and prognosis to provide help.