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自从世界卫生组织(WHO)推行乙型肝炎(乙肝)病毒疫苗免疫以来,全世界新生儿乙肝患病率及乙肝病毒(hepatitis B virus,HBV)携带率平均下降约80%以上。乙肝疫苗的安全性、免疫原性和保护性已得到全世界公认。但疫苗接种后有10%的成人不产生应答,另有5%~10%的接种者抗HBs水平低于有
Since the World Health Organization (WHO) launched the Hepatitis B (HBV) vaccine, the prevalence of hepatitis B and the carrying rate of hepatitis B virus (HBV) worldwide have dropped by more than 80% on average. The safety, immunogenicity and protectiveness of hepatitis B vaccine have been universally recognized. However, 10% of the adults did not respond after vaccination and another 5% -10% of the vaccinates had lower anti-HBs levels than