Efficacy and safety of ginkgo injections in the treatment of angina pectoris caused by coronary hear

• 作 者: Tan Di Wu Jiarui Jing Zhiwei D
• 机 构: Department of Clinical Pharmacology of Traditional Chinese Medicine, School of Chinese Materia Medic
• 出 处: 中医杂志（英文版）
• 发表日期: 2019年3期
• 关键词: Ginkgo injections Angina pectoris Network Meta-analysis Systematic review

OBJECTIVE:To assess the clinical efficacy and safety of ginkgo injections (Gls) combined with conventional treatment (CT) against angina pectoris (AP) due to coronary heart disease (CHD).METHODS:Randomized controlled trials (RCTs) that used Gls to treat AP were searched in SinoMed,PubMed,China National Knowledge Infrastructure Database,Chinese Scientific Joals Database,Wanfang Database,Embase and Cochrane Library until March 2017.The Cochrane risk of bias method was used to evaluate the methodological quality of RCTs.Data were analyzed using Stata v13.1 and WinBUGS v1.4.3.RESULTS:A total of 73 RCTs involving 7621 patients were included.A Bayesian network Meta-analysis of RCTs was undertaken,and the advantages of four types of Gl-supplemented CT in AP treatment were determined.CONCLUSION:Gl-assisted CT was more effective against AP than CT alone.However,based on the limitations of the study,additional high-quality RCTs are required to confirm our findings.