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临床医生很早就注意到营养不良与严重创伤后不良的临床结局之间存在相关性。1936年Studley在研究因胃十二指肠溃疡而手术的患者时,发现术前6个月体重减轻超过20%的患者和体重减轻少于20%的患者,术后死亡率分别是33%和3%。以后的许多临床观察均证实了Studley
Clinicians have long noticed a correlation between malnutrition and the clinical outcome of severe post-traumatic events. Studying for patients with gastroduodenal ulcers in 1936 Studley found that patients who lost more than 20% of their body weight and lost less than 20% 6 months prior to surgery had postoperative mortality rates of 33% and 3%. Many future clinical observations confirm Studley