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我们应用寡核苷酸芯片技术,分别筛选Burkitt’s淋巴瘤(BL)和皮肤T细胞淋巴瘤(CTCL)细胞系细胞与正常淋巴细胞间差异表达的基因,并对其功能进行初步的分析。材料和方法1 寡核苷酸探针的设计 芯片所包括的基因来源主要有:①Alizadeh等[1 ] 从1785 6条基因中筛选出的与恶性淋巴
We used oligonucleotide microarray technology to screen differentially expressed genes between Burkitt’s lymphoma (BL) and cutaneous T-cell lymphoma (CTCL) cell lines and normal lymphocytes, respectively, and preliminary analysis of their function. Materials and methods 1 Oligonucleotide probe design Genes included in the chip are mainly: ① Alizadeh et al [1] selected from the 1785 6 genes and malignant lymph