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目的 :统计我院 2 0 0 1～ 2 0 0 3年抗菌药物的应用情况 ,分析抗菌药物使用的特点和趋势。方法 :采用WHO药物统计合作中心设定的限定日剂量 (defineddailydose ,DDD)方法计算我院抗菌药物的用药频度和药物利用指数。 结果 :青霉素、头孢菌素类、大环内酯类使用频率较高 ,罗红霉素和头孢曲松的使用频率上升较快。青霉素、复方磺胺甲唑唑、阿莫西林、甲硝唑等仍为我院常用品种。结论 :抗菌药物中头孢菌素和青霉素为主流用药 ,新一代大环内酯类将成为应用和发展较快的品种。DUI >1的品种约占 1/ 4 ,说明部分抗菌药物有过量使用的现象
OBJECTIVE: To analyze the application of antibacterials in our hospital from 2001 to 2003 and to analyze the characteristics and trends of the use of antibacterials. Methods: The defined daily dosage (defineddailydose, DDD) method set by WHO Cooperative Drug Statistics Center was used to calculate the frequency and drug utilization index of antibacterials in our hospital. Results: The frequency of penicillins, cephalosporins and macrolides was higher, and the use frequency of roxithromycin and ceftriaxone increased rapidly. Penicillin, sulfamethoxazole compound azole, amoxicillin, metronidazole and other commonly used in our hospital varieties. Conclusion: Cephalosporin and penicillin are the main drugs in the antibacterial drugs. The new generation of macrolides will be applied and developed rapidly. DUI> 1 species accounted for about 1/4, indicating that some antimicrobial drugs overuse