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目的:探讨肺及支气管原发性粘液表皮样癌临床病理特点。方法:收集江门市中心医院5例肺及支气管原发性粘液表皮样癌患者的临床资料、病理学检查结果,并结合相关文献进行分析。结果:5例患者平均年龄43岁,临床症状以支气管刺激及阻塞症状为主。2例组织学分级为高度恶性型,预后较差;3例为低度恶性型,其中2例预后较好。结论:肺及支气管原发性粘液表皮样癌是一种罕见疾病,临床预后与病理分级、临床分期密切相关,需与唾液腺型肿瘤等多种疾病鉴别。
Objective: To investigate the clinicopathological features of primary mucoepidermoid carcinoma of lung and bronchi. Methods: The clinical data and pathological findings of 5 patients with primary mucoepidermoid carcinoma of the lung and the bronchi in Jiangmen Central Hospital were collected and analyzed with related literatures. Results: The average age of 5 patients was 43 years. The main clinical symptoms were bronchial irritation and obstruction. Two cases were classified as highly malignant with poor prognosis and three with low grade of malignancy, of which two had good prognosis. Conclusions: Lung and bronchial primary mucoepidermoid carcinoma is a rare disease. The clinical prognosis is closely related to the pathological grade and clinical stage, and needs to be distinguished from salivary gland tumors and other diseases.