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颅内外动脉吻合首例施行于1967年。以后的10年内这种手术被广泛采用。为了检验此手术对有症状的颈内动脉(ICA)和/或大脑中动脉(MCA)动脉粥样硬化病人的治疗价值,1977年开始了颅内-颅外动脉吻合(EC/IC搭桥)的国际合作研究。选送病人从1977年8月19日到1982年9月30日,最后随访于1985年3月完成。本文介绍了有关研究方法和入选病人的特点。一、研究目的及组织为了确定颞浅动脉(STA)与MCA吻合对有症状的、手术所不能及的(动脉内膜切除)ICA及MCA动脉粥样硬化性狭窄或闭塞的病人,能否起到减少卒中和与卒中有关的死亡问题。本研究由美国神经传染病及卒中国立研究所投资,并有加拿大、日本等国参加。成立筹划指导委员会,方法中心及临床中心协作实施此项研究。
The first case of intracranial and external arterial anastomosis was performed in 1967. This procedure is widely adopted in the next 10 years. To test the value of this procedure for the treatment of patients with symptomatic ICA and / or MCA atherosclerosis, intracranial-extracranial arterial anastomosis (EC / IC bypass) was initiated in 1977 International cooperation research. Patient selection from August 19, 1977 to September 30, 1982, the final follow-up in March 1985 completed. This article describes the characteristics of research methods and selected patients. First, the purpose and organization of the study in order to determine the temporal superficial artery (STA) and MCA symptomatic and surgical inaccessibility (endarterectomy) ICA and MCA atherosclerotic stenosis or occlusion of patients, can play To reduce stroke and stroke-related deaths. This study was funded by the National Institute of Neurosurgical and Stroke National Institutes of Health and participated in Canada, Japan and other countries. Establishment of a planning steering committee, method center and clinical center to collaborate on this research.